Adie Syndrome
Synonyms
Adie's Syndrome
Holmes Adie Syndrome
Holmes-Adie Syndrome
Poorly Reacting Pupil
Poorly Reacting Pupils
Pupil, Poorly Reacting
Pupils, Poorly Reacting
Syndrome, Adie
Syndrome, Adie's
Syndrome, Holmes-Adie
A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)