Antibody-Dependent Cell Cytotoxicity
Synonyms
ADCC
Antibody Dependent Cell Cytotoxicity
Antibody-Dependent Cell Cytotoxicities
Antibody-Dependent Cell Cytoxicities
Antibody-Dependent Cell Cytoxicity
Cell Cytotoxicities, Antibody-Dependent
Cell Cytotoxicity, Antibody-Dependent
Cell Cytoxicities, Antibody-Dependent
Cell Cytoxicity, Antibody Dependent
Cell Cytoxicity, Antibody-Dependent
Cytotoxicities, Antibody-Dependent Cell
Cytotoxicity, Antibody Dependent Cell
Cytotoxicity, Antibody-Dependent Cell
Cytoxicities, Antibody-Dependent Cell
Cytoxicity, Antibody-Dependent Cell
The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.