Ataxia Telangiectasia Mutated Proteins
Synonyms
A T Protein
A-T Protein
AT Mutated Protein
ATM Protein
Mutated Protein, AT
Protein, A-T
Protein, AT Mutated
A group of PROTEIN-SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.