Ataxin-2

Synonyms

ATXN2 Protein

Ataxin 2

Ataxin 2 Protein

Ataxin-2 Protein

Atx 2 Protein

Atx-2 Protein

Protein, ATXN2

Protein, Ataxin-2

Protein, Atx-2

Protein, SCA2

SCA2 Protein

Spinocerebellar Ataxia Type 2 Protein

A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.