Autophagy-Related Protein-1 Homolog

Synonyms

Autophagy Related Protein 1 Homolog

Serine Threonine Protein Kinase ULK1

Serine-Threonine Protein Kinase ULK1

ULK1 Protein

Unc 51 Like Autophagy Activating Kinase 1

Unc 51 Like Kinase 1

Unc-51 Like Autophagy Activating Kinase 1

Unc-51-Like Kinase 1

A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates.