Bartter Syndrome
Synonyms
Aldosteronism with Hyperplasia of the Adrenal Cortex
Bartter Disease
Bartter's Disease
Bartter's Syndrome
Bartters Disease
Bartters Syndrome
Juxtaglomerular Hyperplasia with Secondary Aldosteronism
Syndrome, Bartter
Syndrome, Bartter's
A group of disorders caused by defective salt reabsorption in the ascending LOOP OF HENLE. It is characterized by severe salt-wasting, HYPOKALEMIA; HYPERCALCIURIA; metabolic ALKALOSIS, and hyper-reninemic HYPERALDOSTERONISM without HYPERTENSION. There are several subtypes including ones due to mutations in the renal specific SODIUM-POTASSIUM-CHLORIDE SYMPORTERS.