beta-Mannosidase

Synonyms

beta D Mannosidase

beta Mannanase

beta Mannosidase

beta-D-Mannosidase

beta-Mannanase

manA protein (beta-Mannosidase)

An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.