Brugada Syndrome
Synonyms
Brugada ECG Pattern
Brugada Syndrome 1
Brugada Type ECG Pattern
ECG Pattern, Brugada
Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome
Sudden Unexplained Death Syndrome
Sudden Unexplained Nocturnal Death Syndrome
Sudden Unexplained Nocturnal Death Syndrome (SUNDS)
An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.