DAX-1 Orphan Nuclear Receptor
Synonyms
DAX 1 Orphan Nuclear Receptor
DSS AHC Critical Region on the X Chromosome, Gene 1 Protein
DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein
NR0B1 Protein
Nuclear Receptor 0B1
Nuclear Receptor DAX 1
Nuclear Receptor DAX-1
Nuclear Receptor NR0B1
Nuclear Receptor Subfamily 0, Group B, Member 1
An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.