DNA Restriction-Modification Enzymes

Synonyms

DNA Restriction Modification Enzymes

Enzymes, DNA Restriction-Modification

Modification Systems, Restriction

Restriction Modification Systems

Restriction-Modification Enzymes, DNA

Restriction-Modification Systems

Systems, Restriction Modification

Systems, Restriction-Modification

Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.