DNA Topoisomerases, Type II
Synonyms
DNA Topoisomerase (ATP-Hydrolysing)
DNA Topoisomerase II
DNA Type 2 Topoisomerase
Topoisomerase II
Type II DNA Topoisomerase
DNA TOPOISOMERASES that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex.