Dystonin
Synonyms
230 240 kDa Bullous Pemphigoid Antigen
230 kDa Bullous Pemphigoid Antigen
230-240 kDa Bullous Pemphigoid Antigen
Bullous Pemphigoid Antigen 1
Hemidesmosomal Plaque Protein
A plakin characterized by repeat sequences homologous to SPECTRIN and PLECTIN and C-terminal EF HAND MOTIFS. It functions as an integrator of INTERMEDIATE FILAMENTS, ACTIN and MICROTUBULES in cytoskeleton networks. It is required for anchoring intermediate filaments to the actin cytoskeleton in neural and muscle cells as well as anchoring KERATIN-containing intermediate filaments to HEMIDESMOSOMES in EPITHELIAL CELLS.