Endothelin-1
Synonyms
Big Endothelin
Big Endothelin 1
Big Endothelin-1
Endothelin 1
Endothelin Type 1
Endothelin, Big
Endothelin-1, Big
Precursor, Proendothelin-1
Preproendothelin
Preproendothelin 1
Preproendothelin-1
Proendothelin (1-38)
Proendothelin 1 Precursor
Proendothelin-1 Precursor
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)