Globosides
Synonyms
Cytolipins
Lacto N neotetraosylceramide
Lacto N tetraosylceramide
Lacto-N-neotetraosylceramide
Lacto-N-tetraosylceramide
Lactoneotetraosylceramide
Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.