Group III Phospholipases A2
Synonyms
Group III Secretory Phospholipase A2
Phospholipase A2 III
Phospholipase A2-III
Phospholipases A2, Group III
A subcategory of secreted phospholipases A2 with specificity for PHOSPHATIDYLETHANOLAMINES and PHOSPHATIDYLCHOLINE. It occurs as a component of VENOMS and as a mammalian secretory phospholipase A2. The creation of this group is based upon similarities in the structural determinants of the enzymes including a long amino-terminal domain, a conserved group III-specific domain, and a long carboxyl-terminal domain.