Hydrochlorothiazide
Synonyms
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide
Dichlothiazide
Dihydrochlorothiazide
Esidrex
Esidrix
HCTZ
HydroDIURIL
Hypothiazide
Oretic
Sectrazide
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.