Immunoglobulin Switch Region
Synonyms
Heavy-Chain Mu Switch Region
Ig Switch Sequence
Ig Switch Sequences
Immunoglobulin Switch Regions
Region, Immunoglobulin Switch
Regions, Immunoglobulin Switch
Sequence, Ig Switch
Sequences, Ig Switch
Switch Region, Immunoglobulin
Switch Regions, Immunoglobulin
Switch Sequence, Ig
Switch Sequences, Ig
A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during IMMUNOGLOBULIN CLASS SWITCHING. Ig switch regions are found on genes encoding all five classes (IMMUNOGLOBULIN ISOTYPES) of IMMUNOGLOBULIN HEAVY CHAINS.
See Also