Inositol 1,4,5-Trisphosphate

Synonyms

1,4,5-IP3

1,4,5-InsP3

D-myo-Inositol, 1,4,5-tris(dihydrogen phosphate)

Inositol 1,4,5-Triphosphate

Myo-Inositol 1,4,5-Trisphosphate

Myoinositol 1,4,5-Triphosphate

Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.