Iron Regulatory Protein 1
Synonyms
ACO1 Protein
Aconitase 1, Soluble
Ferritin Repressor Protein
IRE BP1
IRE-BP1
IRP 1 Protein
IRP-1 Protein
IRP1 Protein
Repressor Protein, Ferritin
Soluble Aconitase 1
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.