Jumonji Domain-Containing Histone Demethylases

Synonyms

JmjC Domain Containing Histone Demethylases

JmjC Domain-Containing Histone Demethylases

Jumonji Domain Containing Histone Demethylases

A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.