Leukemia, Large Granular Lymphocytic

Synonyms

Aggressive NK Cell Leukemia

Aggressive Natural Killer Cell Leukemia

Granular Lymphocytoses, Large

Granular Lymphocytosis, Large

LGL Leukemia

LGL Leukemias

Large Granular Lymphocyte Leukemia

Large Granular Lymphocytoses

Large Granular Lymphocytosis

Leukemia, LGL

Leukemia, Lymphocytic, Large Granular

Leukemia, NK LGL

Leukemia, NK-LGL

Leukemia, Natural Killer Cell Large Granular Lymphocytic

Leukemia, T Cell Large Granular Lymphocytic

Leukemia, T LGL

Leukemia, T-Cell Large Granular Lymphocytic

Leukemia, T-LGL

Leukemias, LGL

Leukemias, NK-LGL

Leukemias, T-LGL

Lymphocytoses, Large Granular

Lymphocytosis, Large Granular

Lymphoproliferative Disease of Granular Lymphocytes

Lymphoproliferative Disease of Large Granular Lymphocytes

NK Cell Large Granular Lymphocytic Leukemia

NK LGL Leukemia

NK-Cell Large Granular Lymphocytic Leukemia

NK-LGL Leukemia

NK-LGL Leukemias

Natural Killer Cell Large Granular Lymphocytic Leukemia

T Cell Large Granular Lymphocyte Leukemia

T Cell Large Granular Lymphocytic Leukemia

T LGL Leukemia

T-Cell Large Granular Lymphocyte Leukemia

T-Cell Large Granular Lymphocytic Leukemia

T-LGL Leukemia

T-LGL Leukemias

A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.