Leukodystrophy, Globoid Cell

Synonyms

Cell Leukodystrophies, Globoid

Cell Leukodystrophy, Globoid

Cell Leukoencephalopathies, Globoid

Cell Leukoencephalopathy, Globoid

Classic Globoid Cell Leukodystrophy

Deficiencies, GALC

Deficiencies, Galactocerebrosidase

Deficiencies, Galactosylceramide beta-Galactosidase

Deficiency Disease, Galactosylceramidase

Deficiency Disease, Galactosylceramide-beta-Galactosidase

Deficiency Diseases, Galactosylceramidase

Deficiency Diseases, Galactosylceramide-beta-Galactosidase

Deficiency, GALC

Deficiency, Galactocerebrosidase

Deficiency, Galactosylceramide beta-Galactosidase

Diffuse Globoid Body Sclerosis

Disease, Galactosylceramidase Deficiency

Disease, Galactosylceramide-beta-Galactosidase Deficiency

Diseases, Galactosylceramidase Deficiency

Diseases, Galactosylceramide-beta-Galactosidase Deficiency

Early Onset Globoid Cell Leukodystrophy

Early-Onset Globoid Cell Leukodystrophy

GALC Deficiencies

GALC Deficiency

Galactocerebrosidase Deficiencies

Galactocerebrosidase Deficiency

Galactosylceramidase Deficiency Disease

Galactosylceramidase Deficiency Diseases

Galactosylceramide Lipidosis

Galactosylceramide beta Galactosidase Deficiency

Galactosylceramide beta Galactosidase Deficiency Disease

Galactosylceramide beta-Galactosidase Deficiencies

Galactosylceramide beta-Galactosidase Deficiency

Galactosylceramide-beta-Galactosidase Deficiency Disease

Galactosylceramide-beta-Galactosidase Deficiency Diseases

Galactosylcerebrosidase Deficiency

Galactosylsphingosine Lipidosis

Globoid Body Sclerosis, Diffuse

Globoid Cell Leukodystrophies

Globoid Cell Leukodystrophy

Globoid Cell Leukoencephalopathies

Globoid Cell Leukoencephalopathy

Globoid Leukodystrophies

Globoid Leukodystrophy

Infantile Globoid Cell Leukodystrophy

Krabbe Disease

Krabbe Leukodystrophy

Krabbe's Disease

Krabbe's Leukodystrophy

Krabbes Disease

Krabbes Leukodystrophy

Late Onset Globoid Cell Leukodystrophy

Late-Onset Globoid Cell Leukodystrophy

Leukodystrophies, Globoid

Leukodystrophies, Globoid Cell

Leukodystrophy, Globoid

Leukodystrophy, Globoid Cell, Classic

Leukodystrophy, Globoid Cell, Early-Onset

Leukodystrophy, Globoid Cell, Infantile

Leukodystrophy, Globoid Cell, Late-Onset

Leukodystrophy, Krabbe

Leukodystrophy, Krabbe's

Leukoencephalopathies, Globoid Cell

Leukoencephalopathy, Globoid Cell

Psychosine Lipidosis

beta-Galactosidase Deficiencies, Galactosylceramide

beta-Galactosidase Deficiency, Galactosylceramide

An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.