Lewy Body Disease
Synonyms
Cortical Lewy Body Disease
Dementia, Lewy Body
Diffuse Lewy Body Disease
Lewy Body Dementia
Lewy Body Disease, Cortical
Lewy Body Disease, Diffuse
Lewy Body Type Senile Dementia
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
See Also