Loss of Heterozygosity
Synonyms
Allelic Loss
Allelic Losses
Heterozygosity Loss
Heterozygosity, Loss of
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.
See Also