Mismatch Repair Endonuclease PMS2
Synonyms
PMS 2 Protein
PMS-2 Protein
PMS1 Homolog 2, Mismatch Repair Protein
PMS2 Protein
Postmeiotic Segregation Increased S. cerevisiae 2
Postmeiotic Segregation Increased-S. cerevisiae-2
A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.