Mucopolysaccharidosis II
Synonyms
Deficiency, I2S
Deficiency, Iduronate 2-Sulfatase
Deficiency, Iduronate Sulfatase
Deficiency, Sulfoiduronate Sulfatase
Gargoylism, Hunter Syndrome
Hunter Syndrome
Hunter Syndrome Gargoylism
Hunter's Syndrome
Hunters Syndrome
I2S Deficiency
Iduronate 2 Sulfatase Deficiency
Iduronate 2-Sulfatase Deficiency
Iduronate Sulfatase Deficiency
Mucopolysaccharidosis 2
Mucopolysaccharidosis Type 2
Mucopolysaccharidosis Type II
Sulfoiduronate Sulfatase Deficiency
Syndrome, Hunter
Syndrome, Hunter's
Systemic lysosomal storage disease marked by progressive physical deterioration and caused by a deficiency of L-sulfoiduronate sulfatase. This disease differs from MUCOPOLYSACCHARIDOSIS I by slower progression, lack of corneal clouding, and X-linked rather than autosomal recessive inheritance. The mild form produces near-normal intelligence and life span. The severe form usually causes death by age 15.