Myotonin-Protein Kinase
Synonyms
DM Kinase
DM Protein Kinase
DM-Kinase
DM1PK Protein
DMPK Protein
Kinase, DM Protein
Kinase, Myotonin-Protein
MDGP Protein
MDPK Protein
Myotonic Dystrophy Protein Kinase
Myotonin Protein Kinase
Protein Kinase, DM
Protein, DM1PK
Protein, DMPK
Protein, MDGP
Protein, MDPK
Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1.
See Also