Neoplastic Syndromes, Hereditary

Synonyms

Cancer Syndrome, Hereditary

Cancer Syndromes, Hereditary

Hereditary Cancer Syndrome

Hereditary Cancer Syndromes

Hereditary Neoplastic Syndrome

Hereditary Neoplastic Syndromes

Neoplastic Syndrome, Hereditary

Syndrome, Hereditary Cancer

Syndrome, Hereditary Neoplastic

Syndromes, Hereditary Cancer

Syndromes, Hereditary Neoplastic

The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.