Patched-2 Receptor
Synonyms
PTCH2 Protein
Patched 2 Protein
Patched 2 Receptor
Patched Homolog 2
Patched Homolog-2
Patched Receptor 2
Patched Receptor-2
Patched-2 Protein
Receptor, Patched-2
A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.