Philadelphia Chromosome

Synonyms

1 Chromosomes, Ph

Chromosome, Ph 1

Chromosome, Ph1

Chromosome, Philadelphia

Chromosomes, Ph 1

Chromosomes, Ph1

Ph 1 Chromosome

Ph 1 Chromosomes

Ph1 Chromosome

Ph1 Chromosomes

An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).