Phosphoenolpyruvate Sugar Phosphotransferase System

Synonyms

Hexose Phosphotransferases, Phosphoenolpyruvate

Phosphoenolpyruvate Glycose Phosphotransferase System

Phosphoenolpyruvate Hexose Phosphotransferases

Phosphoenolpyruvate-Glycose Phosphotransferase System

Phosphotransferase System, Phosphoenolpyruvate-Glycose

Phosphotransferases, Phosphoenolpyruvate Hexose

System, Phosphoenolpyruvate-Glycose Phosphotransferase

The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of ADENYLYL CYCLASES. EC 2.7.1.-.