Proprotein Convertase 9
Synonyms
Convertase 9, Proprotein
NARC 1 Protein
NARC-1 Protein
Neural Apoptosis Regulated Convertase 1
Neural Apoptosis-Regulated Convertase 1
Proprotein Convertase, Subtilisin Kexin Type 9
Proprotein Convertase, Subtilisin-Kexin Type 9
A proprotein convertase that is essential for CHOLESTEROL homeostasis. It binds to and is required for the lysosomal degradation of the LDL RECEPTOR (LDLR); the VLDL receptor, and the APOLIPOPROTEIN E RECEPTOR. It also regulates neuronal APOPTOSIS.