Proto-Oncogene Proteins c-met
Synonyms
HGF Receptor
Hepatocyte Growth Factor Receptor
MET Proto Oncogene, Receptor Tyrosine Kinase
MET Proto-Oncogene, Receptor Tyrosine Kinase
MET Receptor Tyrosine Kinase
Proto Oncogene Proteins c met
Proto-Oncogene Proteins, met
Receptor, HGF
Receptor, Hepatocyte Growth Factor
Receptor, Scatter Factor
Scatter Factor Receptor
c Met Receptor Tyrosine Kinase
c met Proteins
c-Met Receptor Tyrosine Kinase
c-met Proteins
met Proto Oncogene Proteins
met Proto-Oncogene Proteins
Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.