Receptor, Serotonin, 5-HT1D
Synonyms
5 HT1D Receptor
5 Hydroxytryptamine1D Receptor
5-HT(1D) Receptor
5-HT(1Dalpha) Receptor
5-HT1D Receptor
5-HT1Dalpha Receptor
5-Hydroxytryptamine1D Receptor
Receptor, 5-HT1D
Receptor, 5-Hydroxytryptamine1D
Receptor, Serotonin 1D
Receptor, Serotonin 1Dalpha
Receptors, Serotonin 1D
Serotonin 1D Alpha Receptor
Serotonin 1D Receptor
Serotonin 1D Receptors
Serotonin 1Dalpha Receptor
Serotonin 1Dalpha Receptors
A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.