Receptors, Tumor Necrosis Factor, Member 14
Synonyms
Entry Mediator, Herpesvirus
HVEM Protein
Herpesvirus Entry Mediator
HveA Protein
Tumor Necrosis Factor Receptor Subfamily, Member 14
Tumor Necrosis Factor Receptor Superfamily, Member 14
A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.