Refsum Disease, Infantile
Synonyms
Disease, Infantile Refsum
Disease, Infantile Refsum's
Infantile Form of Phytanic Acid Storage Disease
Infantile Phytanic Acid Storage Disease
Infantile Refsum Disease
Infantile Refsum's Disease
Infantile Refsums Disease
Refsum Disease, Infantile Form
Refsum's Disease, Infantile
Refsums Disease, Infantile
An early onset form of phytanic acid storage disease with clinical and biochemical signs different from those of REFSUM DISEASE. Features include MENTAL RETARDATION; SENSORINEURAL HEARING LOSS; OSTEOPOROSIS; and severe liver damage. It can be caused by mutation in a number of genes encoding proteins involving in the biogenesis or assembly of PEROXISOMES.