Sarcosine Dehydrogenase

Synonyms

Dehydrogenase, Monomethylglycine

Dehydrogenase, Sarcosine

Monomethylglycine Dehydrogenase

N-Demethylase, Sarcosine

Sarcosine N Demethylase

Sarcosine N-Demethylase

A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.