Sialic Acid Binding Ig-like Lectin 3
Synonyms
Antigen, CD33
Antigens, CD33
CD33 Antigen
CD33 Antigens
Glycoprotein gp67
Sialic Acid Binding Ig like Lectin 3
Siglec-3
gp67, Glycoprotein
A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.