Signaling Lymphocytic Activation Molecule Family Member 1
Synonyms
Antigen, CD150
CD150 Antigen
CDw150 Protein
SLAM Protein
SLAM Receptor
SLAMF1 Protein
SLAMF1 Receptor
A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.