Sp1 Transcription Factor

Synonyms

Specificity Protein 1 Transcription Factor

Transcription Factor, Sp1

Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.