Tuberculosis, Multidrug-Resistant
Synonyms
Drug-Resistant Tuberculosis
MDR Tuberculosis
Multi-Drug Resistant Tuberculosis
Multidrug-Resistant Tuberculosis
Tuberculosis, Drug Resistant
Tuberculosis, Drug-Resistant
Tuberculosis, MDR
Tuberculosis, Multi Drug Resistant
Tuberculosis, Multi-Drug Resistant
Tuberculosis, Multidrug Resistant
Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.