Tuftsin

Synonyms

L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-

L-Thr-L-Lys-L-Pro-L-Arg

L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine

Taftsin

N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.