V-Set Domain-Containing T-Cell Activation Inhibitor 1

Synonyms

B7H4 Immune Costimulatory Protein

Immune Costimulatory Protein B7 H4

Immune Costimulatory Protein B7-H4

T Cell Costimulatory Molecule B7x

T-Cell Costimulatory Molecule B7x

V Set Domain Containing T Cell Activation Inhibitor 1

A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION.