Von Hippel-Lindau Tumor Suppressor Protein
Synonyms
VHL Tumor Suppressor Protein
Von Hippel Lindau Tumor Suppressor Protein
A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME.