2',5'-Oligoadenylate Synthetase

Synonyms

(2'-5')An Polymerase

2',5' Oligoadenylate Polymerase

2',5' Oligoadenylate Synthetase

2',5'-Oligo(A) Polymerase

2',5'-Oligo(A) Synthetase

2',5'-Oligoadenylate Polymerase

2,5 Oligoadenylate Polymerase

2,5 Oligoadenylate Synthetase

2-5A Synthetase

ATP-(2'-5')oligo(A)adenylyltransferase

Oligoadenylate Polymerase, 2,5

Oligoadenylate Synthetase, 2,5

Polymerase, 2',5'-Oligoadenylate

Polymerase, 2,5 Oligoadenylate

Synthetase, 2',5'-Oligoadenylate

Synthetase, 2,5 Oligoadenylate

An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.