2-Isopropylmalate Synthase
Synonyms
2 Isopropylmalate Synthase
3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating)
Synthase, 2-Isopropylmalate
Synthase, alpha-Isopropylmalate
alpha Isopropylmalate Synthase
alpha-Isopropylmalate Synthase
An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12.