Amiloride
Synonyms
Alphapharm Brand of Amiloride Hydrochloride
Amidal
Amiduret Trom
Amiloberag
Amiloride Hydrochloride
Amiloride Hydrochloride, Anhydrous
Amrad Brand of Amiloride Hydrochloride
Anhydrous Amiloride Hydrochloride
Berolina Brand of Amiloride Hydrochloride
Cahill May Roberts Brand of Amiloride Hydrochloride
Douglas Brand of Amiloride Hydrochloride
Hydrochloride, Amiloride
Hydrochloride, Anhydrous Amiloride
Kaluril
Merck Brand of Amiloride Hydrochloride
Merck Sharp & Dohme Brand of Amiloride Hydrochloride
Midamor
Midoride
Modamide
Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-
Trom, Amiduret
Trommsdorff Brand of Amiloride Hydrochloride
A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)