Apolipoprotein C-II
Synonyms
Apo C II
Apo C-II
ApoC2
Apolipoprotein C 2
Apolipoprotein C II
Apolipoprotein C-2
Apolipoprotein CII
Apoprotein C II
Apoprotein C-II
A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.
See Also