Basement Membrane
Synonyms
Basal Lamina
Basal Laminas
Basement Lamina
Basement Laminas
Basement Membranes
Lamina, Basal
Lamina, Basement
Laminas, Basal
Laminas, Basement
Membrane, Basement
Membranes, Basement
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.