BRCA2 Protein
Synonyms
BRCA2 Gene Product
Breast Cancer 2 Gene Product
Breast Cancer 2 Protein
FANCD1 Protein
Fanconi Anemia Complementation Group D1 Protein
Fanconi Anemia Group D1 Complementing Protein
Fanconi Anemia Group D1 Protein
A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)